Monocytes and mental health- big connection!
Monocytes one of the white blood cells usually first and
last on scene for infection and inflammation. Research shows they have a very
close relationship with the digestive system, so good at reflecting chronic
inflammation there.
Monocytes are a big
deal in terms of white cells and cytokine production. Now Cytokines and mental
health big connection! So we shouldn't be surprised to learn monocyctes and
mental health big connection! but not only do you often seen elevated
monocyctes in many mental health presentations, now the research is telling us
that their monocytes are even more inflammatory! Than your monocytes or my
monocytes.
So its the double whammy you
have more of them, more often, and we also see this up regulation of
inflammatory and immune activating genes.
So its like you have these monocyres on steroids, and the
last really interesting piece of information is not only are they kind of mega
inflammatory but there is evidence these monocytes have damaged
Corticosteroids.
Scale back, what does that mean?.. well all white cells have
receptors for cortisol because cortisol has a very important role with immune
regulating, now if those receptors are not working well its like they can't
hear the cortisol.
So what does that effectively mean? When cortisol is saying
“hey guys cut back too much inflammation!” the monocytes are mute and can't
hear the cortisol!!
This is a really interesting area coming up a lot with
mental health and the incredible interaction between the immune system and our
mental wellbeing.
This information can really be an access point to help people
with anxiety and depression and many mental health conditions.
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